aminoglycoside antibiotics

aminoglycoside antibiotics
Group of antibiotics active against many aerobic Gram negative and some Gram positive bacteria. Composed of two or more amino sugars attached by a glycosidic linkage to a hexose nucleus; polycationic and highly polar compounds. Inhibit bacterial protein synthesis by binding to a site on the 30S ribosomal subunit thereby altering codon-anticodon recognition. Common examples are streptomycin, gentamycin, amikacin, kanamycin, tobramycin, netilmicin, neomycin, framycetin.

Dictionary of molecular biology. 2004.

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  • aminoglycoside antibiotics — (am ī no gli ko saīd) A group of antibiotics synthesized by Streptomyces and Micromonospora, which contain a cyclohexane ring and amino sugars; all aminoglycoside antibiotics bind to the small ribosomal subunit and inhibit protein synthesis …   Dictionary of microbiology

  • Aminoglycoside — An aminoglycoside is a molecule composed of a sugar group and an amino group. [MeshName|Aminoglycosides] Several aminoglycosides function as antibiotics that are effective against certain types of bacteria. They include amikacin, gentamicin,… …   Wikipedia

  • aminoglycoside —  ̷ ̷ ¦ ̷ ̷  ̷ ̷ ˌ noun ( s) Etymology: amin + glycoside : any of a group of antibiotics (as streptomycin and neomycin) that inhibit bacterial protein synthesis and are active especially against gram negative bacteria * * * /euh mee noh gluy keuh… …   Useful english dictionary

  • aminoglycoside — Any one of a group of bacteriocidal antibiotics derived from species of Streptomyces or Micromonosporum and characterized by two or more amino sugars joined by a glycoside linkage to a central hexose; aminoglycosides act by causing misreading and …   Medical dictionary

  • aminoglycoside — /euh mee noh gluy keuh suyd , am euh noh /, Pharm. adj. 1. of or pertaining to amino sugars in glycosidic linkage. n. 2. any of a group of bacterial antibiotics having aminoglycoside structure. [AMINO + GLYCOSIDE] * * * …   Universalium

  • Staphylococcus aureus — Scanning electron micrograph of S. aureus, 20,000 times enlargement, false color added Scientific classification Domain: Bacteria …   Wikipedia

  • Cystic fibrosis — Classification and external resources A breathing treatment for cystic fibrosis, using a mask nebuliser and a ThAIRapy Vest ICD 10 E …   Wikipedia

  • Neomycin — Systematic (IUPAC) name (1R,2R,3S,4R,6S) 4,6 diamino 2 Clinical data Trade names Neo rx …   Wikipedia

  • Netilmicin — Systematic (IUPAC) name (2R,3R,4R,5R) ​2 ​{[(1S,2S,3R,4S,6R) ​4 ​amino ​3 ​{[(2S,3R) ​3 ​amino ​6 ​(aminomethyl) ​3,4 ​dihydro 2H ​pyran ​2 ​yl]oxy} ​6 ​(ethylamino) ​2 ​hydroxycyclohex …   Wikipedia

  • Gentamicin — Systematic (IUPAC) name (3R,4R,5R) 2 {[(1S,2S …   Wikipedia

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